Sky Journal of Medicines and Medical Sciences Vol. 7(4), pp. 020-025, May, 2021, Available online,

ISSN 2315-8808 ©2021 Sky Journals


Full Length Research Paper

The prevalence of HIV seropositivity in late pregnancy in a cohort of antenatal attendees with seronegative status at booking in Awka, South-East Nigeria

Umeobika J. C.1*, Ojiyi E. C.2, Ezenyeaku C. T.1, Ezebialu U.I1 and Akabuike J. C.1


1Department of Obstetrics and Gynaecology, Chukwuemeka Odumegwu Ojukwu University Teaching Hospital (COOUTH) Awka, Anambra State, Nigeria.
2Department of Obstetrics and Gynaecology Imo State University Teaching Hospital (IMSUTH) Orlu, Imo State, Nigeria.


*Corresponding author. E-mail:  Tel.: +2348033308765.


Accepted  7 April, 2021




Human Immunodeficiency Virus (HIV) infection remains a major pandemic of public health importance. Paediatric HIV contributes significantly to the world HIV burden. The majority of these pediatric infections (90%) are acquired through mother-to-child transmission during pregnancy, labor and breastfeeding. Routine Counselling and Testing (RCT) for HIV booking forms the entry point for the prevention of mother to child transmission of HIV (PMTCT). In areas with a high prevalence of HIV infection like our country, repeat HIV testing in late pregnancy is advocated. This guideline is not strictly adhered to in some centres. This study sought to determine the late pregnancy HIV status of women who previously tested negative. This was a prospective study involving 194 women. HIV screening of these women was done at booking and late pregnancy. The socio-demographic characteristics of these women were collected using a semi-structured questionnaire. The data was analyzed using SPSS version 15.0. The study gave an HIV seroconversion rate of 4.12% (8/194). The modal age range of participants was 25-29 years (25.77%) while the majority had tertiary education (50.0%). The HIV seroconversion rate of 4.12% from this study is quite high. These were people who would have missed the intrapartum and postpartum PMTCT interventions. Strict adherence to the guideline of repeat HIV testing in late pregnancy should be advocated.

Key words: HIV, seroconversion, pregnant women, prevalence, Awka, Nigeria.


Full Text PDF (197KB)





Search for author names and article from Pubmed:

Umeobika JC

Akabuike JC

Search for author names and article from Google Scholar
Umeobika JC

Akabuike JC